Research

• Isolation and characterization of biologically important proteins, glycoproteins, peptides, glycopeptides, and glycolipides;

• Conventional and enzymatic catalyzed synthesis of biological active peptides;

• Photosensitizing and fluorescent dyes in red and far-red spectra region - synthesis and studies of their main properties as diagnostic and therapeutic agents;

• Development of the so called photodynamic method, based on the photochemical processes, for inactivation of bacteria and viruses in clinical practice and ecology;

• Fluorescent probes, based on the highly conjugated compounds, like phthalocyanines and derivatives, for study of the protein's structures;

• Immobilization of biocatalysts, modification of natural oils and investigation of lipase inhibitors for medical and cosmetics purposes;

• Isolation and purification of enzymes from microbial origin for nutrient and fodder purposes and cosmetics;

• Preparation of technology for protein hydrolysates with designed properties for application in medicine and sport as food additives;

• Application of fluorescent methods for determination of antioxidant activity of biological materials;

• Production and characterization of novel materials (hemocyanins) for prevention of virus infection;

• Evaluation of the antioxidant potential of natural objects by means of spectrophotometric and fluorometric methods. Investigation of the impact of the oxidative stress on the properties of connective tissue proteins. Modification of known methods for proving of dye substances and traces of leather in archaeological and museum objects for the purposes of the conservation analysis.

Laboratory members

Head:

Assoc. Prof. Maya Guncheva, PhD

02 9606 160

408

Maya.Guncheva@orgchm.bas.bg

Name	Room	Phone	Е-mail*
Assoc. Prof. Maya Guncheva, PhD, Head	408	160	Maya.Guncheva
Prof. Pavlinka Dolashka-Angelova, DsC	403	163	Pavlina.Dolashka
Assoc. Prof. Aleksandar Dolashki, PhD	417	155	Alexandar.Dolashki
Assoc. Prof. Vanya Mantareva, DsC	211	181	Vanya.Mantareva
Assoc. Prof. Lyudmila Velkova, PhD	403	163	Lyudmila.Velkova
Assoc. Prof. Miroslav Rangelov, PhD	201	161	Miroslav.Rangelov
Assist. Prof. Dancho Yordanov, PhD	418	175	Dancho.Yordanov
Assist. Prof. Yuliana Raynova, PhD	216	190	Yuliana.Raynova
Assist. Prof. Boryana Yakimova, PhD	408	160	Boryana.Yakimova
Dimitar Kaynarov, chemist	403	163	Dimiter.Kaynarov
Assist. Karina Marinova	403	163	Karina.Marinova
Assist. Petar Petrov	418	175	Petar.Petrov
chemist Venceslav Atanasov	403	163	Ventseslav.Atanasov
chemist Diana Braykova	211	181	Diana.Braykova
Plamen Hristov, chemist	214	174	Plamen.Hristov
Proletina Kardaleva, chemist	417	155	Proletina.Kardaleva
Associated members
Assoc. Prof. Ivan Angelov, PhD	211	181	Ivan.Angelov
Assoc. Prof. Krassimira Idakieva, PhD	216	190	Krasimira.Idakieva
Prof. Ivanka Stoineva, DsC	217	160	Ivanka.Stoineva
Prof. Petar Nedkov, DsC	214	192	pnedkov

*The e-mail is formed after adding '@ orgchm.bas.bg' to the name

PROJECTS

SELECTED GROUP PUBLICATIONS(Q1):

2018

Metallomics,
10,
659-678

Interaction of Na⁺, K⁺, Mg²⁺ and Ca²⁺ counter cations with RNA