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LABORATORY BULGARIAN NMR CENTRE

 

Head

Professor Svetlana Simova PhD, DSc

Laboratory "Bulgarian NMR Centre"
Institute of Organic Chemistry
with Centre of Phytochemistry
Acad. G. Bonchev, Build. 9
Sofia 1113, Bulgaria
tel. +359 2 9606 140
fax +359 2 8700 225
e-mail: sds@orgchm.bas.bg
website

Research activities and expertise

  • Structure analysis and stereochemistry – structure analysis of small and medium size molecules – conformation and configuration; stereochemistry of compounds with central and planar chirality; new synthetic and natural biologically active compounds and mixtures - flavones, terpenoids, alkaloids, carbohydrates, antibiotics, nucleotides, fats and oils etc.; chemical profiling and plant metabolomics, steric interactions by 13С NMR spectroscopy; structure and chemistry of phosphorus-containing compounds;
  •  Molecular mobility – classic dynamic NMR (CLSA), determination of exchange rate constants and thermodynamic parameters in complex multisite exchange systems, tautomeric and conformational equilibria, fluxtional isomerisation; NMR relaxation methods; diffusion NMR spectroscopy (DOSY) for mixture analysis;
  • Supramolecular aggregates and complexes – Diffusion ordered NMR spectroscopy (DOSY) for the investigation of molecular self-assembly, aggregation phenomena, interactions and structure of complex fluids, and nanoscale materials with high compositional and morphological complexity, e.g. colloidal systems, including complex surfactant, surfactant-polymer solutions and emulsions, liposomes, polymeric micelles and functionalised hybrid materials, with potential application as drug delivery systems.
  • Soft materials - HRMAS NMR of polymeric hydrogels and ionic liquids; diffusion NMR spectroscopy for drop size distribution analysis in emulsions;
  • Solid state NMR - basic solid state NMR experiments; Investigation of electrode materials for lithium and sodium ion batteries, complex oxides, ceramics, mesoporous materials and zeolites;
  • Computer programs for automatic analysis of multiplets; signal to noise enhancement in NMR spectra; determination of correlation times and activation energies of the overall and internal molecular reorientation; 13С chemical shifts prediction for natural compounds using spectral databases.

WebSite

 

Personnel

NAME

ROOM

PHONE

E-MAIL

Head
Prof. DSc Svetlana Simova

104

9606-140
Assoc. Prof. Dr. Bozhana Mikhova
103
9606-120 
112 
9606-172
Prof. Dr. Pavletta Shestakova (Denkova)
209
9606-136
Assist. Prof. Dr. Yavor Mitrev
106
9606-146
Assist. Prof. Dr. Alexander Kantardjiev
117
9606-189
Assist. Dr. Miroslav Dangalov
112 
9606-172 
Technician Dessislava Gerginova
103
9606-120 


Copyright ©2012 Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Science. All rights reserved.
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