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WEB MAIL |
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Prof. DSc Peter Nikolov
Institute of Organic Chemistry
with Centre of Phytochemistry
Bulgarian Academy of Sciences
Acad. G. Bonchev Street,
Bl. 9
1113 Sofia, Bulgaria
Tel.: +359 (2) 96 06 147
Fax: +359 (2) 87 00 225
E-mail: petnik@orgchm.bas.bg |
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1944 Born in Obnova, Bulgaria.
1976 M.Sc., Faculty of Physics, University of Sofia.
1984 Ph.D., Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia.
1988 Associate Professor at the Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences.
2001 D.Sc., Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences.
2003 Professor at the Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences.
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Expertise |
Electronic spectroscopy of organic molecules containing heteroatoms.
Photophysical study of biologically active compounds. |
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Current Research |
Electronic spectroscopy of organic molecules containing heteroatoms.
Dual fluorescence and early excited state dynamics of some pyrylium salts.
Excimer fluorescence from acridine and diaza heterocyclic hydrocarbons in non-polar media at low temperatures.
Spectroscopic proves for activated fluorescence and intermolecular hydrogen bonds formation in the singlet excited state of heteroaromatic organic luminophores, containing carbonyl group.
Photophysics properties of new organic materials with possible application in the asymmetrical catalysis, in the nanotechnologies and as optical sensing indicators.
Photophysical study of biologically active compounds
Photophysical properties of new photosensitising agents for decontamination of microbiologically polluted water.
A search for proper photosensitizers which selectively target mitochondria.
Discrimination between two steps in the mitochondrial permeability transition process.
Fluorescence studies on denaturation and stability of recombinant
human interferon-gamma.
Spectroscopic characterization of the structure and conformational stability of different classes of hemocyanins in solution.
Electronic spectroscopy of proteolitic enzymes ( subtiliases and related proteinases, esperase, savinase ) aiming to determinate the local environment and the unfolding processes.
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Visiting Fellowships |
Poland - 1978
Austria - 1985, 1988, 1990
England - 1985
Italy - 1987, 1993, 2002, 2003
Germany, 1980, 1982, 1983, 1990, 1995
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Membership in Scientific Organizations
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Member of the Bulgarian Society of Physics.
Member of the Union of Chemists in Bulgaria.
Founding Member of the non-profit legal entity "Bulgarian Society for Organic and Metaloorganic Chemistry", founded in March 2004 with the purpose to disseminate scientific results and to support young scientists.
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Selected Publications |
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P.Nikolov, F.Fratev, I.Petkov, P.Markov "Dimer Fluorescence of Some b- Dicarbonyl Compounds" Chem.Phys.Letters, v.83, N1, p.170 - 173 (1981)
P.Nikolov, F.Fratev, St.Mintchev "A New Class of Organic Luminophores with a Stilbene Chromophore:
3-phenylmethylene-1(3H)-Isobenzofuranones" Z.Naturforsch., 38a, p.200 - 205 (1983)
P.Nikolov, F.Fratev, O.E.Polansky "Correlations of the 0-0 Transition, the Absorption and Fluorescence Maxima with the s - Hammett Constants " J.Molecular Structure, 114, p.265 - 268 (1984)
T.Deligeorgiev, P.Nikolov, N.Tyutyulkov "Syntheses, Structure and Spectral Properties of Pyrylium Salts and their Derivatives. I. 5,6-Dihydro-benzo(c)-Xantylium Salts" Z.Naturforsch., 42a, p.43 - 48 (1987)
N.Genov, P.Nikolov, C.Betzel, K.Wilson, P.Dolashka "Fluorescence Properties of Subtilisins and Related Proteinases (Subtilases): Relation to X-Ray Models" J.Photochem.Photobiol. B: Biol., 18, p.265 - 272 (1993)
F.Ricchelli, P.Nikolov, S.Gobbo, G.Jori, G.Moreno, C.Salet "Interaction of Phthalocyanines With Lipid Membranes: A Spectroscopic and Functional Study on Isolated Rat Liver Mitochondria" Biochim.Biophys.Acta, 1196, p.165-171 (1994)
P.Nikolov, H.Goerner "Excimer Fluorescence from Acridine and Diaza Heterocyclic Hydrocarbons in
Non-Polar Media at Low Temperatures", J.Photochem.Photobiology A:Chem., 101, 137 - 144 (1996)
I.Timtcheva, P.Nikolov, N.Stojanov, St.Mintchev "Deactivation Processes of the Excited States of
3-hetarylmethylene-1(3H)-isobenzofuranones in Solution. Possibility for Formation of Intermolecular Hydrogen Bonds", J.Photochem.Photobiology A:Chem., 101, p. 145-150 (1996)
D. Georgieva, P.Nikolov, C.Betzel "Steady-state and Time-resolved Fluorescence of Esperase: Comparison with the X-Ray Structure in the Region of the Two Tryptophans" Spectrochimica Acta, Part A, 54,
p.1109-1116 (1998)
D.Nikolova, P.Nikolov, V.Ivanova, A.Gusterova and C.Betzel "Fluorescence Properties of Savinase: the
X-Ray Structure in the Region of the Tryptophyl Residues" Spectrochimica Acta, Part A, 55, p. 2309-2319 (1999)
P.Nikolov, St. Metzov "Peculiarities in the Photophysical Properties of some 6 Styryl 2, 4- Disubstituted Pyrylium Salts" J.Photochem.Photobiol. A:Chem., 135, p. 13-25 (2000)
J.Schutz, P.Dolashka, R.Abrashev, P.Nikolov, W.Voelter "Isolation and Spectroscopic Characterization of the Structural Subunits of Keyhole Limpet Hemocianin" Biochimica et Biophysica Acta, 1546, p.325-336 (2001)
P.Di Muro, M.Beltramini, P.Nikolov, I. Petkova, B.Salvato, F.Ricchelli "Fluorescence Spectroscopy of the Tryptophan Microenvironment in Carcinus aestuarii Hemocyanin" Z.Naturforsch., 57C, p. 1084 - 1091 (2002)
D.Nikolova, N.Genov, P. Nikolov, B.Aleksiev, K.Rajashankar, W.Volter, C.Betzel "Structure Function Relationships In The Neurotoxin Vipoxin From The Vanom Of Vipera Ammodytes Maridionatis" Spectrochimica Acta, Part A, 59, P. 617 - 627 (2003)
P.Christova, K.Todorova, I. Timcheva, G.Nacheva, A.Karshikoff, P.Nikolov "Fluorescence Studies on Denaturation and Stability of Recombinant Human Interferon-Gamma" Z.Naturforshung, 58C, p. 288 294 (2003)
I.Petkova, P. Nikolov, St.Metzov "Steady State and Dynamic Photophysical Properties of
2-Benzoimidazole- acetonitrile - alpha- Phenylmethylenes and 1-Aryl - 2,2 - Dicyanoethenes" Z.Naturforsch., 59A, p.91 - 96 (2004)
D.Georgieva, D.Schwark, P.Nikolov, K.Idakieva, K.Parvanova, K.Dierks, N.Genov, C.Betzel
"Conformational States of the Rapana thomasiana Hemocyanin and its
Substructures Studied by Dynamic Light Scattering and Time Resolved Fluorescence Spectroscopy"
Biophysical Journal, v.88, p.1276 - 1282 (2005)
P.Dolashka, A.Dolashki, S.Stevanovic, R.Hristova, B.Atanasov, P.Nikolov, W.Voelter "Structure and Stability of Arthropodan Hemocyanin Limulus Polyphemus" Spectrochimica Acta, Part A, v. 61 (6),
p.1207 1217 (2005)
F. Ricchelli, G.Jori, S.Gobbo, P. Nikolov, V.Petronilli "Discrimination between two steps in the mitochondrial permeability transition process" International Journal of Biochemistry & Cell Biology 37(9):p. 1858-1868
(2005)
K. Idakieva, N. Siddiqui, K. Parvanova, P. Nikolov, C. Gielens "Fluorescence properties and conformational stability of the
-hemocyanin of Helix pomatia" Biochimica et Biophysica Acta, 1764, p.807 - 814 (2006)
A.Pigliucci, P.Nikolov, A.Rechman, L.Gagliardi, Ch.Cramer, E. Vauthey "Early Excited State Dynamics of
6-Styryl-Substituted Pyrylium Salts Exhibiting Dual Fluorescence" J. Physical Chemistry A 110 (33), p.9988 9994 (2006)
V. Bojinov, N. Georgiev, P. Nikolov "Synthesis And Photophysical Properties Of Fluorescence Sensing Ester- And Amidoamine-Functionalized 1,8-Naphthalimides" J.Photochem.Photobiol. A: Chem.193,
p. 29 - 138 (2008)
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