Research |
The basic research topics are in the interdisciplinary field of the structural organic analysis, carried out experimentally (by means of vibrational spectroscopy and X-ray diffraction) as well as theoretically (on the basis of modern non-empirical quantum-chemical methods). The research object is a large series of organic compounds (medicines, food additives, strong poisons etc., including isotope labelled ones), their hydrogen-bonded complexes as well as anions-intermediates in important chemical reactions. The results obtained make it possible to follow the spectral and structural variations, caused by the conversion of organic molecules into complexes and anions.
าhe scientific expertise of the Group of Molecular Electronic Spectroscopy covers experimental investigations (UV-VIS absorption, steady-state and dynamic luminescent spectroscopy in different media) and quantum chemical studies as well for elucidation the relationship of the chemical and electronic structure of conjugated organic compounds containing heteroatom with the processes of radiative and nonradiative deactivation of their singlet and triplet electronically excited states. The photophysical and photochemical properties of more than 800 organic compounds and dyes are studied, including pyrazolones, oxazolones, benzthiazoles, triazoles, benzopyranes, benzylidenephthalides, indanediones, indenones, coumarines and izo-coumarines, naphthiridines, perylene dyes acridines, pyrylium and xanthilium dyes, porphyrins, merocyanine and asymmetric monomethincyanine dyes, etc.
Our research is directed to possible application of the studied compounds as fluorescent laser dyes, pH sensors, fluorescent markers for polymers, biopolymers and nanoparticles, OLEDs, photosensibillizators for photodynamic therapy of cancer or cleaning of waste waters and structural characterization of biomolecules as well.
The research topics of the Group of Vibrational spectroscopy are:
infrared linear dichroism of molecules oriented in nematic liquid crystal matrices;
infrared ellipsometric studies of thin films and self-assembled monolayers on metallic and silicon surfaces;
vibrational circular dichroism studies of DNA oligonucleotides. Influence of different factors: base sequence, pH, salt concentration and interactions with drugs on the DNA structure and conformation. |
