PROGRAMME

 

Wednesday (October, 3)

 

                                               Chair: Andrey Karshikoff

9:30 Welcome: Director of Institute of Organic Chemistry, Bulgarian Academy of Sciences

9:45 - 10:30  Constantin Craescu (France) Molecular Interactions in the Nucleotide Excision Repair
10:30 – 11:30  Wei Liu (Sweden) Stress Response in Archaea and Eukarya: Structural Studies of Heat Shock Transcription Factors
11:30 - 11:45 Coffee break
11:45 - 12:30 Stefan Stefanovic (Germany)  Protein antigens in tumor diagnosis and therapy       
12:30 – 14:00 Lunch
                                              Chair: Petya Christova

14:00 – 14:45 Ilian Jelesarov (Switzerland) Meet to fold: The peculiar folding of oligomeric proteins

14:45 – 15:30 Andrey Karshikoff (Sweden) Salt bridges and conformational flexibility: effect on protein stability

15:30 - 16:00 Coffee break

16:00–17:00 Rudolf Ladenstein (Sweden) Ionic Interactions in Proteins from Hyperthermophiles: Dynamic Arrangement and Individual Contributions to Stability

17:00 – 18:00 Students ask questions, teachers answer

18:00 Welcome buffet

 

Thursday (October, 4)

 

                                        Chair: Jacqueline Cherfils

10:00 - 11:00 Christine Ebel (France) Stabilization of solubilized membrane proteins

11:00 - 11:15 Coffee break

11:15 – 12.00  J.Luis Arrondo (Spain) Infrared Spectfroscopy. A tool to study protein structure and dynamics

12:00 – 13:45 Lunch

                                               Chair: Constantin Craescu

13:45 – 14:30 Stefan Szedlacsek (Rumania) The short story of the largest thiamine pyrophosphate-dependent enzyme
14:30 – 15:15 András Dér (Hungary) Salts, interfacial water and protein conformation

15:15 – 15:30 Coffee break

15:30-16:30 Jacqueline Cherfils (France) In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors

16:30 – 18:00  Poster session                                 

 

 

Friday (October 5)

 

                                               Chair: Ilian Jelesarov

10:00 – 11:00 Jozef Van Beeumen (Belgium) Standard techniques and recent developments in mass spectrometric analysis of proteins

11:00 - 11:15 Coffee break

11:15 – 12:15 Plamen Demirev (USA) Quantitative proteomics

12:15 – 13:45 Lunch

                                               Chair: Rudolf Ladenstein

13:45 – 14:30 Nikolay Todorov (England) Fragment-based drug discovery: methods and applications

14:30 – 15:15 Maria Miteva (France) Hierarchical structure-based virtual screening for drug design

15:15 – 15:30 Coffee break

15:30 – 16:15 Liliane Mouawad (France) Molecular dynamics of proteins

16:30 – 17:30 Students ask questions, teachers answer

18:00 Good-bye buffet

 

Saturday (October, 6)

 

9:00 – 19:00   Sighseeing tour of  Koprivshtiza and Starossel (Lunch included)